Computational immunologist · Scientist
Marina
Terekhova
I use large-scale single-cell and multi-omic data to understand how the human immune system changes with age, health, and disease.
Decoding human immunity at scale.
My path into science began from two different directions. I first trained as a Medical Doctor, driven by an interest in human health and disease, and later pursued a Master's degree in Computer Science to develop the computational tools needed to answer increasingly complex biological questions.
Currently, I am a Senior Scientist in the Department of Pathology & Immunology at Washington University School of Medicine in St. Louis. My work combines computational biology, immunology, and multimodal data to map immune-cell states and identify the biological programs that shape human aging.
I develop and apply reproducible analytical frameworks for scRNA-seq, CITE-seq, TCR/BCR sequencing, ATAC-seq, spatial data, and plasma proteomics: from cohort-scale study design to biological interpretation.
Human immune aging
Rethinking inflammaging across human diversity
Multidimensional profiling of human T cells reveals high CD38 expression marking recent thymic emigrants and age-related naive T cell remodeling
Single-cell atlas of healthy human blood unveils age-related loss of NKG2C+GZMB−CD8+ memory T cells and accumulation of type 2 memory T cells
A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune populations
Research · Collaboration · Ideas